2025 Summer Intern - Translational Pharmacokinetics and Pharmacodynamics

2025 Summer Intern - Translational Pharmacokinetics and Pharmacodynamics

Department Summary

This intern position is in the Translational Pharmacokinetics (PK) & Pharmacodynamics (PD) or tPKPD Department within Development Sciences. The tPKPD department applies preclinical models (in silico, in vitro or in vivo) to determine the pharmacokinetics (what the body does to the drug) and/or pharmacodynamics (what the drug does to the body) of biotherapeutics. The information obtained from such work is often used to help select lead molecules, optimize dosing regimens andunderstand the PK behavior/metabolic fate of different molecular designs as we help advance molecules through stages of research and into early clinical development. The work within the tPKPD department spans across a wide range of disease areas, including oncology, immunology, ophthalmology, infectious disease and neuroscience.

This internship position is located in South San Francisco on-site.

The Opportunity

The tPKPD department is seeking a highly motivated masters or PhD student interested in drug development and the PK of biologics. The intern will work on investigating how molecular properties and biophysical parameters influence the PK of Antibody-Drug-Conjugates (ADCs), with a focus on the impact of ADC linkers on PK. This role involves collaborating with cross-functional teams to integrate data across portfolio programs to enable prediction of PK behavior of future molecules. The intern will have the opportunity to influence key stakeholders in the advancement of ADC research and contribute to the selection of promising therapeutic candidates.

Program Highlights

• Intensive 12 week, full-time (40 hours per week) paid internship.

• Program start dates are in May/June (Summer)

• A stipend, based on location, will be provided to help alleviate costs associated with the internship.

• Ownership of challenging and impactful business-critical projects.

• Work with some of the most talented people in the biotechnology industry.

Who You Are (Required)

Required Education:

- Must be pursuing a Master's Degree (enrolled student).

- Must be pursuing a PhD (enrolled student).

Required Majors: Biomedical engineering, bioengineering, biology, chemical engineering, bioinformatics/computational biology, or other pharmaceutical sciences fields preferred.

Required Skills:

• Experience with biology-related or bioengineering research

• Proficient in performing literature review

• Proficient with Microsoft Office tools

• Experience with data management and analysis

Preferred Knowledge, Skills, and Qualifications

• Familiarity with PK/PD concepts

• Familiarity with coding in Python, R, and/or MATLAB, with a willingness to explore and learn as needed

• Excellent communication, collaboration, and interpersonal skills.

• Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

Relocation benefits are not available for this job posting.

The expected salary for this position based on the primary location ofSouth San Francisco is $40-$45 hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.