2025 Summer Intern - gRED, Regev Lab

This internship position is located in South San Francisco, on site.

The Opportunity

Cellular deconvolution is a useful technique to infer the unknown composition of bulk RNAseq samples, but has traditionally been limited to estimating abundances of discrete cell types. Recent approaches based on maximum entropy models and generative models show promise inferring continuous processes such as differentiation. The Regev lab aims to develop a deep generative model that builds on these approaches and is trained on massive, comprehensive, and heterogeneous reference atlases containing 10s of millions of single cells from hundreds of studies. Such a model would enable the development of a tool to routinely profile the large volumes of bulk RNAseq data collected in-house. We will assess the accuracy of the method in epithelial, cancer, and other tissue samples containing diverse and continuous cell states.

Program Highlights

• Full time for at least first 12 weeks (40 hours per week) paid internship.

• Program start dates are in June (Summer)

• A stipend, based on location, will be provided to help alleviate costs associated with the internship.

• Ownership of challenging and impactful business-critical projects.

• Work with some of the most talented people in the biotechnology industry.

Who You Are

Required Education

- Must be pursuing a PhD Degree (enrolled student).

Required Majors

Biological & Computational Sciences.

Required Skills

• Ability to lead and design computational analyses to address biological questions.

Preferred Qualifications

• Experience with analysis of single cell or spatial transcriptomic data.

• Familiarity with state-of-the art tools.

• Knowledge and experience with deep generative models.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of California is $50.00 hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.