Head of Site Operations

At Eisai, satisfying unmet medical needs and increasing the benefits healthcare provides to patients, their families, and caregivers is Eisai's human health care (hhc) mission. We're a growing pharmaceutical company that is breaking through in neurology and oncology, with a strong emphasis on research and development. Our history includes the development of many innovative medicines, notably the discovery of the world's most widely-used treatment for Alzheimer's disease. As we continue to expand, we are seeking highly-motivated individuals who want to work in a fast-paced environment and make a difference. If this is your profile, we want to hear from you.

Genetics Guided Dementia Discovery (G2D2) Overview:

Eisai has been dedicated for decades to the pursuit of novel therapeutics to improve the lives of people suffering from dementia and their families. Recognizing the potential for human genetics, data sciences and precision chemistry to disrupt the drug discovery paradigm, Eisai launched the Eisai Center for Genetics Guided Dementia Discovery (G2D2) in 2019 to accelerate the discovery of innovative therapeutics. G2D2 is a unique drug discovery organization driven by a diverse group of passionate, dedicated and collaborative scientists committed to one goal: delivering breakthroughs for patients and their families. All Eisai employees, as part of the company's human health care (hhc) mission, spend at least 1% of their working time with patients and families to ensure that the innovation we drive is based on an understanding of their real needs.

A historical strength of G2D2, driven by insights from human genetics, is immunodementia: targeting immune-related targets for dementia. Expanding from this strength to additional themes in the biology of neurodegenerative disorders, we focus not only on how human genetics and other human biology data may identify and validate therapeutic targets with increased likelihood of success in clinical trials, but also how this data guides selection of the best approaches to design new therapeutics and deliver them to the right patient at the right time. Recognizing the obvious alignment between human genetics and nucleic acid modalities, our precision chemistry strategy is to validate human biology hypotheses by utilizing our unique RNA-targeting therapeutic platform. G2D2's expertise in harnessing molecular complexity (stereochemistry and topology) to successfully discover and develop natural product-based therapeutics has been applied to create an evolving unique nucleic acid therapeutic platform that is being employed globally in multiple clinical and pre-clinical programs at Eisai.

G2D2's cutting-edge 50,000-square-foot facility is strategically located in Cambridge, MA, to accelerate collaborations with leading research institutes in this world-class biotech hub. Our facility is designed around an open-lab concept, enabling scientists with multi-disciplinary backgrounds to work together in a single integrated lab space. Our labs include state-of-the-art capabilities that support the variety of disciplines located at the site, including medicinal and process chemistry, in-vitro and in-vivo biology, microscopy, DMPK, drug safety, chemical and structural biology, automation and screening, and more. G2D2 is home to Eisai's global capabilities in discovery data science as well as other global Eisai functions, including global health, DMPK, drug safety, and IP, thus providing a rich environment for cross-functional interaction.

More information about G2D2 can be found at https://us.eisai.com/our-science/g2d2

The Head of Site Operations at G2D2 will be working collaboratively with site leadership to formulate and continuously refine a strategy for facility administration in support of the delivery of high-quality research outcomes.

Responsibilities include but are not limited to:

• Managing the Site Operations team and budget to coordinate routine facility maintenance and operational activities for the laboratory and vivarium.
• Ensuring all facilities maintenance and operations are conducted with appropriate safety, environmental and regulatory compliance.
• Maintaining and continuously refining site program for environmental health and safety (EH&S).
• Proactively proposing and executing a capital expenditure strategy that will enable G2D2 to meet its research goals.
• Directing efforts to foster a positive site culture and manage effective use of common spaces.
• Leading outreach with key community stakeholders, including neighborhood biotech and community organizations.
• Leading large-scale projects relating to Site Operations as needed, potentially including major renovation or construction efforts, moves, etc.
• Tracking environment-related data and consider ways to continuously improve the site's environmental footprint.
• Maintaining relationships with counterparts at other global R&D sites to explore and proposing measures that could lead to synergy (cost savings from vendor centralization, alignment regarding work standards, etc.), and consult on project at other facilities as needed.
• Representing G2D2 as an active participant in the Global R&D EH&S Committee.

Essential Functions:

• Managing the Site Operations team and resources, including budget, to maintain effective functioning of research activities, including facilities maintenance, ordering/shipping/receiving supplies, and coordinating with vendors.
• Managing contract resources to maintain environmental health and safety, including waste disposal and lab safety.
• Planning and facilitating programs to foster site morale, including teambuilding, lunch catering, holiday-themed events, etc.
• Undertaking short- and long-term strategic planning for site operations, including space planning, capital investment, and other projects.
• Maintaining relationships with stakeholders and representing Eisai and the G2D2 site in various forums, including through meetings involving local site leadership, counterparts at other global Eisai sites, and other members of the Cambridge biopharma community.

Scope Measures:

• Managing site facilities budget
• Participating in and drive major projects as needed, potentially including for sites beyond G2D2
• Making prompt decisions regarding employee safety independently
• Executing facility operations in line with the health and safety policies to secure safety operations and support active research activities
• Directing employees, consultants, and contractors for key programs and maintaining responsibility for ensuring all regulatory compliance

Knowledge/Skills/Abilities Required:

• BS/MS and a minimum of 15 years of directly related experience
• Bachelor's degree in related field required, advanced degree preferred
• Minimum of 15+ years related work experience required, 5+ years supervisory experience
• Excellent business operations and risk management skills
• Excellent leadership, management, and organizational skills
• Excellent communication skills, including cross-cultural/global communication skills
• Experience with pharmaceutical research and development
• Thorough knowledge of federal, state and local environmental health and safety regulations which are necessary to laboratory operations
• Understanding of chemical and biological processes and industrial hygiene experience

Eisai Salary Transparency Language:

Final pay determinations will depend on various factors including but not limited to experience level, education, knowledge, and skills.

Employees are eligible to participate in Company employee benefit programs. For additional information on Company employee benefits programs, visit https://us.eisai.com/careers-at-eisai/benefits.

Certain other benefits may be available for this position, please discuss any questions with your recruiter.

Eisai is an equal opportunity employer and as such, is committed in policy and in practice to recruit, hire, train, and promote in all job qualifications without regard to race, color, religion, gender, age, national origin, citizenship status, marital status, sexual orientation, gender identity, disability or veteran status. Similarly, considering the need for reasonable accommodations, Eisai prohibits discrimination against persons because of disability, including disabled veterans.

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