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Research Post Doc Fellow - Falk Lab

Children's Hospital of Philadelphia
United States, Pennsylvania, Philadelphia
Feb 26, 2025

SHIFT:

Day (United States of America)

A Brief Overview

Assume responsibility for an on-going, innovative research project as a Postdoctoral Fellow at CHOP. Our postdoc experience will broaden your skillset, scientific background, and research capabilities.

CHOP's Commitment to Diversity, Equity, and Inclusion
CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children.

We strongly encourage all candidates of diverse backgrounds and lived experiences to apply.

About the Laboratory

The post-doctoral fellow will join the High Throughput Screening (HTS) Team within the Mitochondrial Medicine Frontier Program. The fellow will be responsible for optimizing existing methods and develop new assays to enable faster genetic and drug library screening for discovery purposes followed by target validation and mechanistic confirmation in many mitochondrial disease models, including C. elegans, zebrafish, and human cell lines. The fellow will also supervise research technicians on the team who will support the fellow in their efforts. The effort of the HTS fellow will support diverse programs across the research lab group, as the HTS team is involved in many of our research projects. Once trained, additional projects may be developed on which the post-doctoral fellow serves as programmatic lead.

The candidate should have interest and ideally experience with assay/protocol development, especially in the context of utilizing high throughput technology such as plate readers, high content imaging, flow cytometry, and liquid handling automation. Prior experience with cell culture, zebrafish, and/or C. elegans is strongly preferred but not required; general experience working in other model organisms is required. Any data analysis/programing experience, such as R or Python, is also preferred but not required. The candidate should be comfortable working independently and with various pieces of technology, as well as integrate well in a team environment and have excellent verbal and written communication skills as well as collaboration skills.

The HTS team will specifically train the fellow on how to use our CX5 plate reader and Agilent Bravo pipetting robot. Training on our models (cell culture, zebrafish, and/or C. elegans) will be provided as needed depending on project needs.

Responsibilities

  • Participate in project planning, recording, and evaluation of data.

  • Conduct independent scholarly research, developing new methods and protocols under the guidance of a mentor (principal investigator).

  • Acquire technical, lab management, and grant writing skills.

  • Participate in seminars, lectures, poster sessions, national presentations, and professional workshops.

  • Supervise junior lab members.

  • Assist with other research projects as needed.

Education

  • Required: Doctorate

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