Post-Doctoral Associate: Dorr Lab

Summary of Position

The Dorr Lab uses Pharmacogenomics, Spatialomics, Genomics, Transcriptomics, Clinical Outcomes, Bioinformatics, Epidemiology, Molecular Cellular Biology and Genetics to investigate mechanisms of kidney disease, allograft complications, Indigenous health and precision medicine.

Our team is seeking a Postdoctoral Associate to establish a new lab with an optimistic lab culture. The immediate need is for cell line engineering (CRISPR, etc), and drug metabolism studies to investigate drug-drug and drug-gene interactions to be translated to clinic. The postdoc may investigate mechanisms of kidney disease with spatialomics, biopsies and clinical data.

This is NOT a remote position.

The postdoc will work with Dr. Dorr's multidisciplinary teams that includes nephrologists, pharmacologists, pathologists, statisticians, geneticists, bioinformaticians, and other collaborators. Dr. Dorr will mentor the Postdoctoral Fellow towards his/her long-term goals.

The position may include the following work. Experience is preferred, but not required for all:

60% Data generation in Lab:
Molecular biology techniques: PCR, molecular cloning, sequencing analysis, CRISPR, base editing, RNA extraction, RNA Seq, RT-PCR, gene cloning, cell line characterization, western blotting, E. coli transformations, plasmid preparations, and characterizations, primer design, etc.
Chemical techniques: drug dilutions, drug-drug interactions, chemical preparations and handling, drug metabolism studies, chemical reactions, making solutions, drug/chemical quantification with LC/MS or other techniques, etc.
Cell culture experience: transfections, microscopy, cryopreservation, drug metabolism assays, soft agar assays, cell viability assays, flow cytometry, passaging of cells, cell maintenance, etc.
Lab: Lab notebook and other databases, ordering supplies
Spatialomics project: work with team to assess biopsies for mechanisms of kidney diseases

20% Data Analysis and Writing
Writing: Manuscript writing, reviewing and editing grants for the PI, make figures and tables
Data analysis: Statistics for drug metabolism assays, spatialomics and clinical data analysis, R

10% Presentations and meetings

10% Lab management, mentoring new lab members, organization

Required Qualifications
1. A PhD, MD, PharmD or equivalent degree with research training in the biological sciences
2. Skills in documentation, recordkeeping and organization
3. Expertise in molecular biology, cell culture techniques and data analysis.
4. Understanding, and preferably experience, of genome engineering such as CRISPR
5. Proficiency in scientific writing as evidenced by publication(s)

Salary will follow the NIH Post-doc salary scale and depend on experience.

Pay Range: $61,000-$74,088; depending on education/qualifications/experience and in alignment with the NIH Post-doc salary scale, dependent on experience.

Please visit the Benefits for Postdoctoral Candidates website for more information regarding benefit eligibility.

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training
• Medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and life insurance
• Employee wellbeing program
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost

To apply: Complete the University's application and submit CV, letter stating why you are a good fit for this position and list 3 references with contact information.

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will have the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

This position will remain open until filled.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

Questions? Contact Dr. Casey Dorr at cdorr@umn.edu

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