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Senior Histotechnologist

Exact Sciences
paid time off
United States, Arizona, Phoenix
445 North 5th Street (Show on map)
Aug 28, 2025

Help us change lives

At Exact Sciences, we're helpingchange how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you're working to help others.

Position Overview

The Senior Histotechnologist (Tuesday - Saturday 12:00pm - 8:30pm) is responsible for performing highly skilled Histology and operational activities in a fast paced and complex operation. The high complexity nature of the work requires excellent attention to detail, effective written and verbal communication skills, the ability to multi-task and be flexible with tasks and schedules, and the ability to work independently in a team environment.

Essential Duties

Include, but are not limited to, the following:

  • Perform complex and nonroutine histology procedures including cutting, microtomy, H&E staining of patient specimens, and execution of IHC assays with appropriate controls on submitted tissue specimens.
  • Assist with writing new procedures and revising procedures.
  • Prepare department for a CAP inspection and stay knowledgeable of the CAP Anatomic Checklist.
  • Act as a resource for technical personnel and respond to workplace questions and concerns.
  • Provides day-to-day direction and guidance to Histotechnologists.
  • Assess the competency of peers as needed.
  • Assist with new employee orientation and training.
  • Maintain stringent standards for quality, identify any issues which might adversely impact the quality of test results and/or employee safety, and immediately communicate these to the appropriate management representatives as necessary for prompt resolution.
  • Conduct and document qualification of incoming reagent lots and instrumentation.
  • Monitor and process the histology queue for various tasks that need to be performed and perform these tasks independently or with minimal supervision.
  • Perform macrodissection of unstained slides in accordance with markings of stained slides provided by pathologists.
  • Prepare reagents, solutions, and controls.
  • Interact with pathologists and support laboratory staff in accordance with standard operating procedures (SOPs) to ensure specimens are processed in a timely manner with high quality.
  • Assist with coordination of pharma services clients on execution of clinical research projects.
  • Assist in the identification of opportunities for histology process improvements, including lab workflows and associated SOPs.
  • Assist in equipment specification, installation, maintenance, and calibration.
  • Provide summary reports on process metrics, as needed.
  • Contribute to preparation and participate in internal/external inspections and audits.
  • Apply and integrate feedback in a professional manner.
  • Provide and receive open and regular feedback and adjust accordingly.
  • Prioritize and drive results with a high emphasis on quality.
  • Display ability to work as part of a team.
  • Adapt to a fast-paced environment.
  • Apply strong communication skills with ability to maintain open communication with internal employees, managers, and customers.
  • Display high attention to detail with strong quality orientation.
  • Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
  • Support and comply with the company's Quality Management System policies and procedures.
  • Maintain regular and reliable attendance.
  • Ability to act with an inclusion mindset and model these behaviors for the organization.
  • Ability to work nights and/or weekends, as needed.
  • Ability to work seated for approximately 20% of a typical working day. Ability to work standing for approximately 80% of a typical working day.
  • Ability to lift up to 25 pounds for approximately 5% of a typical working day.
  • Ability to grasp with both hands; pinch with thumb and forefinger; turn with hand/arm; reach above shoulder height.
  • Ability to comply with any applicable personal protective equipment requirements.
  • Ability to use various types of laboratory equipment; including H&E and IHC stainers, microtomes, tissue water bath, embedding station, cryostat and coverslipper.
  • May perform repetitious actions using lab tools.
  • Ability to use near vision to view samples at close range.
  • May be exposed to hazardous materials, tissue specimens, and instruments with moving parts, lasers, heating and freezing elements, and high-speed centrifugation.
  • May use various chemicals to perform duties.

Minimum Qualifications

  • Associate Degree in a scientific field, 6+ years of laboratory experience or Bachelor Degree in a scientific field, 4+ years of laboratory experience.
  • Proficient in Microsoft Office programs, such as Word, Excel, and PowerPoint.
  • Demonstrated ability to perform the essential duties of the position with or without accommodation.
  • Authorization to work in the United States without sponsorship.

Preferred Qualifications

  • HT (ASCP) or HLT (ASCP) certification.
  • Possession of active QIHC (Qualification in Immunohistochemistry) through the ASCP Board of Certification.
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Salary Range:

$67,000.00 - $119,000.00

The annual base salary shown is for this position located in US - AZ - Phoenix on a full-time basis. In addition, this position is bonus eligible.

Exact Sciences is proud to offer an employee experience that includes paid time off (including days for vacation, holidays, volunteering, and personal time), paid leave for parents and caregivers, a retirement savings plan, wellness support, and health benefits including medical, prescription drug, dental, and vision coverage. Learn more about our benefits.

Our success relies on the experiences and perspectives of a diverse team, and Exact Sciences fosters a culture where all employees can develop personally and professionally with a sense of respect and belonging. If you require an accommodation, please contact us here.

Not ready to apply? Join our Talent Community to stay updated on the latest news and opportunities at Exact Sciences.

We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to disability, protected veteran status, and any other status protected by applicable local, state, or federal law.

To view the Right to Work, E-Verify Employer, and Pay Transparency notices and Federal, Federal Contractor, and State employment law posters, visit our compliance hub. The documents summarize important details of the law and provide key points that you have a right to know.

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