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Principal Analyst, Supply Chain Digital Transformation

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Sep 30, 2025

Job Description

At VERTEX, we are pioneering breakthroughs in biotechnology and committed to ensuring no patient is left behind. As part of our digital transformation journey, we are seeking a Principal Supply Chain Technology Leader to drive innovation across logistics, global trade, labeling, and artwork systems.

In this role, you'll lead digital initiatives that ensure the fast, efficient, and compliant supply of VERTEX medicines from clinical trials to commercial scale across all modalities including small molecules, cell, and gene therapies.

You'll collaborate with global supply chain, quality, IT, and manufacturing teams to deliver cutting-edge solutions that improve visibility, streamline operations, and strengthen compliance. This is a highly impactful role where your work directly supports our mission to transform patients lives through science, medicine, and technology.

What You'll Do:

  • Lead the design, and deployment of digital solutions for logistics, trade, and artwork management.
  • Shape and implement next-generation supply chain platforms, integrated with VERTEX's enterprise data-first architecture.
  • Partner with cross-functional teams to enable faster decision-making, automation, and operational excellence.
  • Ensure systems comply with global regulatory and quality standards while remaining scalable and future ready.
  • Contribute to the development of a digital supply chain control tower for enhanced visibility and performance.

What We're Looking For:

  • Bachelor's degree in supply chain, IT, or related field; Master's a plus.
  • 5+ years of experience in supply chain systems or technology (pharma/biotech preferred).
  • Expertise in SaaS-based supply chain solutions (Logistics, Global Trade, Artwork systems).
  • Strong leadership and problem-solving skills with experience leading cross-functional initiatives.
  • Familiarity with GxP and regulated environments.
  • Bonus: Control tower experience along with exposure to advanced analytics, AI in supply chain space.

Why Join Us:

  • Play a critical role in building the digital backbone of a global biotech supply chain.
  • Work at the intersection of science, technology, and operations with real patient impact.
  • Collaborate in a dynamic, global, and mission-driven culture.
  • Hybrid flexibility with growth opportunities in digital transformation and biotech leadership.

Travel: Up to 10%

Location Requirement: Boston, MA (Hybrid - 3 days onsite)

Pay Range:

$140,700 - $211,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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