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Senior Director, Commercial Technology AI Product Management

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Nov 08, 2025

Job Description

Vertex is seeking a strategic Senior Director to lead AI Product Management within our Commercial Technology organization. This role will be responsible for building and managing a portfolio of high-value commercial AI products that automate operations, accelerate patient access, and enhance customer experience. The Senior Director will define and drive the AI strategy, lead the development and adoption of agentic AI-powered solutions, and collaborate closely with business engagement and platform teams to deliver measurable value. A key focus will be on defining and tracking the impact of AI investments, fostering upskilling and capability building across the functional teams to ensure successful adoption of AI and GenAI capabilities.

Key Duties and Responsibilities

  • Define and lead the AI product vision, roadmap, and lifecycle for commercial technology initiatives.

  • Translate complex business needs into scalable AI solutions that drive measurable value across marketing, market access, and field operations.

  • Partner with Commercial, Data Science, IT, and external stakeholders to identify high-impact AI opportunities aligned with business goals.

  • Lead cross-functional teams through the full product lifecycle-from ideation and design to development, deployment, and optimization.

  • Horizon scan and identify emerging AI technologies, build and manage AI product roadmap, and drive adoption of cutting-edge autonomous commercial solutions.

  • Ensure AI products meet compliance, legal, and ethical standards, including data privacy and regulatory requirements.

  • Champion a culture of innovation, experimentation, and continuous improvement in AI product development.

  • Serve as a trusted advisor to senior leadership, providing insights and recommendations grounded in data and commercial strategy.

Knowledge and Skills

  • Proven expertise in AI/ML product management within a commercial or healthcare technology context.

  • Deep understanding of commercial strategy, market access, and the pharmaceutical value chain.

  • Strong leadership in cross-functional environments, with the ability to influence and align diverse stakeholders.

  • Demonstrated ability to translate business challenges into AI-driven solutions with measurable outcomes.

  • Advanced proficiency in commercial competencies including:

  • Insight Generation: Forecasting, data synthesis, and customer experience insights.

  • Commercial Strategy: Portfolio planning, lifecycle management, and brand value creation.

  • Commercial Execution: Market access planning, vendor management, and performance accountability.

  • Business-Minded Leadership: Risk management, resource allocation, and innovation strategy.

  • Influential Communication: Executive-level storytelling, negotiation, and stakeholder engagement.

  • Trusted Partnership: Cross-functional collaboration and inclusive leadership.

Education and Experience

  • Bachelor's degree in a relevant field (e.g., Business, Computer Science, Engineering); advanced degree (MBA, MS, PhD) preferred.

  • Experience in the biotech, pharmaceutical, or healthcare technology industry strongly preferred.

  • 12+ years' experience with 3+ years pharmaceutical commercial domain experience

  • Strong experience setting agentic AI vision and governance framework development

  • Prior experience building and embedding A.I. into an organization

  • Understanding of multi-agent, hierarchal structures and orchestration e.g. integrating agents and AI solutions with other agents/ platforms across an end-to-end process

  • Hands-on experience with LLM APIs (OpenAI, Anthropic, Azure OpenAI)

  • Fine-tuning and context engineering for domain-specific applications

  • Knowledge of model evaluation and performance optimization techniques

  • Emerging technology evaluation, horizon scanning and partnership management experience

  • Hands-on experience building and deploying agentic AI in Pharma/Life Sciences

  • Change management and technology adoption expertise

  • Executive communication and influence skills

Pay Range:

$0 - $0

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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