Sr Director, Strategic Technologies

Reports to: Executive Director, Commercial & Development Technologies

Overview

Alnylam is the world's leading RNA interference (RNAi) company, pioneering the development of novel therapies that transform the lives of patients. As we advance our commercial and marketing capabilities in the U.S., we are evolving our technology leadership structure to drive enterprise-wide integration, scale, and innovation.

The Senior Director, U.S. Commercial and Marketing Technology will serve as a technology leader for both U.S. Commercial Technology and Marketing Technology. This role unifies data, omnichannel, web, content, and digital engagement platforms to ensure cohesive strategy, operational excellence, and support for Alnylam's next-generation omnichannel model.

This leader will shape and execute the integrated technology vision for U.S. Commercial & Marketing, drive cross-functional alignment, oversee a growing team of product and platform leads, and help guide the delivery of advanced analytics, digital, and AI-enabled capabilities.

Key Responsibilities

Strategic Leadership & Enterprise Alignment

• Serve as the senior technology partner to the U.S. Commercial and Marketing leadership teams, aligning technology strategy to business priorities across Sales, Market Access, Marketing, Patient Services, and Operations.
• Own the unified strategy for Commercial and Marketing technology platforms, ensuring seamless integration across data, omnichannel, web, content, digital engagement, and analytics ecosystems.
• Drive the technology roadmap supporting the company's omnichannel transformation, enabling AI-driven insights, personalization, and digital activation.
• Establish an enterprise-aligned operating model emphasizing centralized governance, platform consolidation, scalability, and consistent standards.

Organizational Leadership & People Management

• Lead and grow a multi-disciplinary team, including emerging platform/product leads (e.g., Web Technology Lead), establishing a clear operating framework, career paths, and accountability structures.
• Oversee cross-functional program delivery for key Commercial and Marketing technology initiatives, ensuring high-quality execution and business adoption.
• Foster a culture of continuous improvement, business partnership, and user-centric design.

Platform Governance, Architecture & Operations

• Provide executive oversight of MarTech and CommercialTech ecosystems, including CRM, customer data platforms, web platforms, content management systems, omnichannel orchestration, analytics environments, and third-party digital tools.
• Oversee platform lifecycle management: requirements gathering, architecture design, vendor governance, implementation, integrations, and ongoing support.
• Reduce fragmentation by consolidating vendor and platform governance and ensuring consistent data, security, privacy, and compliance standards.
• Ensure systems are scalable, high-performing, and aligned with enterprise data and technology principles.

Cross-Functional Collaboration & Influence

• Engage senior stakeholders across U.S. Commercial, Marketing, Corporate Communications, Data & AI, IT Strategy & Operations, Regulatory, and Security to drive integrated planning and decision-making.
• Champion shared governance, portfolio prioritization, and cross-functional alignment to support enterprise-wide digital and data initiatives.
• Drive adoption of advanced analytics, AI, and digital capabilities across Commercial and Marketing teams.

Operational Execution & Continuous Improvement

• Serve as escalation point for complex, cross-functional issues affecting Commercial and Marketing platforms.
• Identify and address gaps in system configuration, data flows, and processes to enhance usability and business value.
• Evaluate emerging technologies and propose investments that improve customer engagement, operational efficiency, and ROI.

Qualifications

• Bachelor's or Master's degree in Information Technology, Computer Science, Data Science, Digital Marketing Technology, or a related field.
• 12+ years of experience in Commercial Technology, Marketing Technology, Digital, Data, or Enterprise IT roles, with increasing leadership responsibilities.
• Significant experience supporting U.S. Commercial and/or Marketing functions in regulated industries (biopharma strongly preferred).
• Strong understanding of CRM, omnichannel engagement, MarTech platforms, web technology, analytics environments, and data governance.
• Proven success leading technology teams, large programs, and complex cross-functional initiatives.
• Demonstrated ability to influence senior leaders and drive enterprise-aligned strategies.
• Excellent communication skills, with the ability to translate technical concepts into business language.
• Strong vendor management, program management, and operational excellence skill sets.
• Ability to balance strategic thinking with hands-on leadership in a dynamic, evolving environment.

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U.S. Pay Range

$226,800.00 - $306,800.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

AboutAlnylam

We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.