Research Associate II - Transgenic Mouse Core

Join the forefront of groundbreaking research at theBeckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

A Research Associate II position is available within the Transgenic Mouse Core where you will perform specialized laboratory procedures to create genetically-modified animal models. This career track position will require a motivated and dedicated individual excited by the prospect of exploring and implementing cutting edge methods and technologies that will advance basic and translational research. This position may start as a Research Associate I dependent upon skills and experience.

The Transgenic/Knockout Program [TKP] produces genetically modified mice as a service to researchers at the City of Hope, and, as such, you must possess a high level of dedication and professionalism.

Ability to perform light work on weekends to set up experiments as required.

As a successful candidate, your will:

* Conduct euthanasia procedures in compliance with ethical and regulatory standards.

* Prepare specialized types of media for cell culture, in vitro embryo culture/manipulation, and cryopreservation of mouse gametes and embryos.

* In vitro Culture of Mouse Embryos.

* Develop proficiency in micro-manipulation techniques and electroporation procedures used to genetically modify mouse embryos.

* Perform both surgical and non-surgical embryo transfer of embryos into mice.

* Manage and maintain in vitro cultures of mouse embryonic stem cells.

* Perform cryopreservation of mouse gametes and embryos.

* Rederivation of mouse strains using in vitro fertilization and embryo transfer.

* Actively manage mouse breeding colonies to ensure their well-being and genetic integrity.

* Molecular Biology such as; PCR, in vitro transcription, gel electrophoresis, and plasmid construction/preparation.

* Conduct microscopy procedures required to generate and genotype genetically-modified mice.

Qualifications:

* Bachelor's degree. Masters degree preferred

* 2+ years of related experience with a Bachelor's degree or 1+ year related experience with a Master's degree.

* Experience with laboratory mice. Previous experience with specific methods is not required, so you must demonstrate both the enthusiasm and dedication required to master a variety of tasks.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here