Research Associate - RI Perinatal Hu

The Hu Lab at the Center for Perinatal Research, Nationwide Children's Hospital/Ohio State University in Columbus, Ohio, is seeking a highly motivated and organized Research Associate with immediate availability. The successful candidate will join Dr. Yan Hu's laboratory to contribute to cutting-edge research on lung epithelial progenitor cell activation and lung tissue repair in chronic lung diseases affecting both children and adults. Our research utilizes transgenic mice, patient-derived lung organoids, single-cell and spatial transcriptomics, and tissue culture techniques to explore molecular mechanisms driving small airway and alveolar repair. The overarching goal of the Hu Lab is to uncover the molecular pathways that regulate lung epithelial progenitor cell function in health and disease, with an emphasis on developing novel therapies to promote lung tissue regeneration in conditions such as COPD, BPD, and beyond. The lab is supported by funding from the NIH/NHLBI and the Abigail Wexner Research Institute.

Interested individuals should send a curriculum vitae and a personal statement to Dr. Yan Hu at Yan.Hu@nationwidechildrens.org

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Manage mouse colonies, including breeding, weaning, genotyping, euthanasia, and coordinating animal purchases and shipments, ensuring meticulous record-keeping.
• Independently perform experiments in accordance with established protocols, which may involve laboratory animals or human lung tissue. Evening and weekend work may occasionally be required.
• Process human lung tissue, maintain cell and tissue cultures, and collect samples such as cells and bronchoalveolar lavage as needed.
• Ensure precision and accuracy in experimental procedures across various research projects.
• Maintain accurate daily logs of experiments and drug usage, including documentation of challenges encountered during studies.
• Analyze data using appropriate statistical methods and prepare reports that include visual representations of the results.
• Assist in writing and preparing scientific publications and grant proposals.
• Order supplies, maintain equipment, and manage the laboratory's inventory, ensuring all research equipment is in working condition.
• Contribute to the preparation of research budgets and ensure studies are conducted within budgetary limits.
• Provide training and guidance to other lab personnel and students in research methodologies, techniques, and equipment use.
• Maintain a clean and organized laboratory environment, adhering to safety protocols.

Qualifications

• Bachelor's degree in biological or related science with at least two years of experience handling laboratory mice.
• Experience in cell culture is strongly preferred.
• Coursework or experience in areas such as anatomy, genetics, physiology, and statistical research methods, especially related to lung research, is desirable.
• Strong organizational skills, attention to detail, and ability to work both independently and as part of a team.

Percent of time spent on:

* 50% Conducting research studies

* 25% Collecting and analyzing data

* 10% Preparing reports, publications and grant proposals

* 05% Resource person for other lab members and investigators

* 05% Mentoring less experienced research personnel

* 05% Purchasing supplies

Minimum Physical Requirements

* 100% Kneeling / reaching

* 100% Finger dexterity

* 100% Talking / hearing / seeing

* 33% Lifting / carrying weight 0-20 pounds for 1-5 minutes